Structure of PDB 1px2 Chain A

Receptor sequence
>1px2A (length=294) Species: 10116 (Rattus norvegicus) [Search protein sequence]
AARVLLVIDEPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGF
SVDMEVLRNGVKVVRSLKPDFVLIRQHAFSMARNGDYRSLVIGLQYAGIP
SVNSLHSVYNFCDKPWVFAQMVRLHKKLGTEEFPLIDQTFYPNHKEMLSS
TTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKTYATAEPFIDAK
YDVRVQKIGQNYKAYMRTWKLEQIAMSDRYKLWVDTCSEIFGGLDICAVE
ALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMTQA
3D structure
PDB1px2 Tetramerization and ATP binding by a protein comprising the A, B, and C domains of rat synapsin I.
ChainA
Resolution2.23 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A E373 E386 E250 E263
BS02 ATP A K225 K269 H274 S275 G276 K279 E305 F307 I308 L375 E386 K114 K158 H163 S164 G165 K168 E194 F196 I197 L252 E263 MOAD: Kd=120nM
Gene Ontology
Biological Process
GO:0007269 neurotransmitter secretion
Cellular Component
GO:0008021 synaptic vesicle

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Cellular Component
External links
PDB RCSB:1px2, PDBe:1px2, PDBj:1px2
PDBsum1px2
PubMed14688264
UniProtP09951|SYN1_RAT Synapsin-1 (Gene Name=Syn1)

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