Structure of PDB 1puf Chain A

Receptor sequence
>1pufA (length=77) Species: 10090 (Mus musculus) [Search protein sequence]
NNPAANWLHARSTRKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLL
NLTERQVKIWFQNRRMKMKKINKDRAK
3D structure
PDB1puf STRUCTURE OF HOXA9 AND PBX1 BOUND TO DNA: HOX HEXAPEPTIDE AND DNA RECOGNITION ANTERIOR TO POSTERIOR
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R203 K207 R209 C210 P211 Y212 R247 Q248 I251 N255 K259 R11 K15 R17 C18 P19 Y20 R55 Q56 I59 N63 K67 PDBbind-CN: Kd=0.23uM
BS02 dna A L200 A202 R209 P211 Y229 R232 R235 Q254 R257 M258 K261 L8 A10 R17 P19 Y37 R40 R43 Q62 R65 M66 K69 PDBbind-CN: Kd=0.23uM
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1puf, PDBe:1puf, PDBj:1puf
PDBsum1puf
PubMed12923056
UniProtP09631|HXA9_MOUSE Homeobox protein Hox-A9 (Gene Name=Hoxa9)

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