Structure of PDB 1ptr Chain A

Receptor sequence
>1ptrA (length=50) Species: 10090 (Mus musculus) [Search protein sequence]
HRFKVYNYMSPTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCREKVANLC
3D structure
PDB1ptr Crystal structure of the cys2 activator-binding domain of protein kinase C delta in complex with phorbol ester.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
2.7.11.13: protein kinase C.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A H231 C261 C264 C280 H1 C31 C34 C50
BS02 ZN A C244 C247 H269 C272 C14 C17 H39 C42
BS03 PRB A Y238 M239 S240 P241 T242 L250 L251 G253 L254 Q257 Y8 M9 S10 P11 T12 L20 L21 G23 L24 Q27
External links
PDB RCSB:1ptr, PDBe:1ptr, PDBj:1ptr
PDBsum1ptr
PubMed7781068
UniProtP28867|KPCD_MOUSE Protein kinase C delta type (Gene Name=Prkcd)

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