Structure of PDB 1poc Chain A

Receptor sequence
>1pocA (length=134) Species: 7460 (Apis mellifera) [Search protein sequence]
IIYPGTLWCGHGNKSSGPNELGRFKHTDACCRTHDMCPDVMSAGESKHGL
TNTASHTRLSCDCDDKFYDCLKNSADTISSYFVGKMYFNLIDTKCYKLEH
PVTGCGERTEGRCLHYTVDKSKPKVYQWFDLRKY
3D structure
PDB1poc Crystal structure of bee-venom phospholipase A2 in a complex with a transition-state analogue.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.1.4: phospholipase A2.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A W8 G10 G12 D35 W8 G10 G12 D35
BS02 GEL A G10 H11 G12 H34 D35 H56 T57 Y87 G10 H11 G12 H34 D35 H56 T57 Y87
Gene Ontology
Molecular Function
GO:0004623 phospholipase A2 activity
GO:0005509 calcium ion binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0047498 calcium-dependent phospholipase A2 activity
Biological Process
GO:0006644 phospholipid metabolic process
GO:0016042 lipid catabolic process
GO:0050482 arachidonate secretion
Cellular Component
GO:0005576 extracellular region

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External links
PDB RCSB:1poc, PDBe:1poc, PDBj:1poc
PDBsum1poc
PubMed2274788
UniProtP00630|PA2_APIME Phospholipase A2

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