Structure of PDB 1pnt Chain A

Receptor sequence
>1pntA (length=157) Species: 9913 (Bos taurus) [Search protein sequence]
AEQVTKSVLFVCLGNICRSPIAEAVFRKLVTDQNISDNWVIDSGAVSDWN
VGRSPDPRAVSCLRNHGINTAHKARQVTKEDFVTFDYILCMDESNLRDLN
RKSNQVKNCRAKIELLGSYDPQKQLIIEDPYYGNDADFETVYQQCVRCCR
AFLEKVR
3D structure
PDB1pnt Crystal structure of bovine heart phosphotyrosyl phosphatase at 2.2-A resolution.
ChainA
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) C12 N15 C17 R18 S19 D129
Catalytic site (residue number reindexed from 1) C12 N15 C17 R18 S19 D129
Enzyme Commision number 3.1.3.2: acid phosphatase.
3.1.3.48: protein-tyrosine-phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PO4 A C12 L13 I16 C17 R18 C12 L13 I16 C17 R18
Gene Ontology
Molecular Function
GO:0003993 acid phosphatase activity
GO:0004721 phosphoprotein phosphatase activity
GO:0004725 protein tyrosine phosphatase activity
GO:0004726 non-membrane spanning protein tyrosine phosphatase activity
GO:0016791 phosphatase activity
Biological Process
GO:0006470 protein dephosphorylation
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1pnt, PDBe:1pnt, PDBj:1pnt
PDBsum1pnt
PubMed7537084
UniProtP11064|PPAC_BOVIN Low molecular weight phosphotyrosine protein phosphatase (Gene Name=ACP1)

[Back to BioLiP]