Structure of PDB 1pi6 Chain A

Receptor sequence
>1pi6A (length=606) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
SSISLKEIIPPQPSTQRNFTTHLSYDPTTNAIAYPCGKSAFVRCLDDGDS
KVPPVVQFTGHGSSVVTTVKFSPIKGSQYLCSGDESGKVIVWGWTFDKES
NSVEVNVKSEFQVLAGPISDISWDFEGRRLCVVGEGRDNFGVFISWDSGN
SLGEVSGHSQRINACHLKQSRPMRSMTVGDDGSVVFYQGPPFKFSASDRT
HHKQGSFVRDVEFSPDSGEFVITVGSDRKISCFDGKSGEFLKYIEDDQEP
VQGGIFALSWLDSQKFATVGADATIRVWDVTTSKCVQKWTLDKQQLGNQQ
VGVVATGNGRIISLSLDGTLNFYELGHDEVLKTISGHNKGITALTVNPLI
SGSYDGRIMEWSSSSMHQDHSNLIVSLDNSKAQEYSSISWDDTLKVNGIT
KHEFGSQPKVASANNDGFTAVLTNDDDLLILQSFTGDIIKSVRLNSPGSA
VSLSQNYVAVGLEEGNTIQVFKLSDLEVSFDLKTPLRAKPSYISISPSET
YIAAGDVMGKILLYDLQSREVKTSRWAFRTSKINAISWKPAEEIEEDLVA
TGSLDTNIFIYSVKRPMKIIKALNAHKDGVNNLLWETPSTLVSSGADACI
KRWNVV
3D structure
PDB1pi6 The structure of Aip1p, a WD repeat protein that regulates Cofilin-mediated actin depolymerization.
ChainA
Resolution2.5 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H368 D370 H367 D369
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0005515 protein binding
GO:0051015 actin filament binding
Biological Process
GO:0030042 actin filament depolymerization
GO:0032466 negative regulation of cytokinesis
GO:0051016 barbed-end actin filament capping
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005884 actin filament
GO:0030479 actin cortical patch
GO:0030864 cortical actin cytoskeleton
GO:0043332 mating projection tip

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1pi6, PDBe:1pi6, PDBj:1pi6
PDBsum1pi6
PubMed12807914
UniProtP46680|AIP1_YEAST Actin-interacting protein 1 (Gene Name=AIP1)

[Back to BioLiP]