Structure of PDB 1pb9 Chain A

Receptor sequence
>1pb9A (length=281) Species: 10116 (Rattus norvegicus) [Search protein sequence]
TRLKIVTIHQEPFVYVKPTMSDGTCKEEFTVNGDPVKKVICTGPNHTVPQ
CCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMG
ELLSGQADMIVAPLTINTERAQYIEFSKPFKYQGLTILVKKGTRITGIND
PRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQ
AVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWK
QNVSLSILKSHENGFMEDLDKTWVRYQECDS
3D structure
PDB1pb9 Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 4AX A F92 T126 R131 S179 S180 W223 D224 F81 T115 R120 S168 S169 W212 D213 MOAD: Ki=241uM
PDBbind-CN: -logKd/Ki=3.62,Ki=241uM
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:1pb9, PDBe:1pb9, PDBj:1pb9
PDBsum1pb9
PubMed12805203
UniProtP35439|NMDZ1_RAT Glutamate receptor ionotropic, NMDA 1 (Gene Name=Grin1)

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