Structure of PDB 1owf Chain A

Receptor sequence
>1owfA (length=96) Species: 562 (Escherichia coli) [Search protein sequence]
ALTKAEMSEYLFDKLGLSKRDAKELVELFFEEIRRALENGEQVKLSGFGN
FDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKSRVENASPK
3D structure
PDB1owf Integration Host Factor: putting a twist on protein-DNA recognition
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A K45 R55 K57 P61 R63 P65 R82 K88 K44 R54 K56 P60 R62 P64 R81 K87 PDBbind-CN: Kd=4.6nM
BS02 dna A G48 N51 K86 G47 N50 K85 PDBbind-CN: Kd=4.6nM
BS03 dna A T4 K5 K57 R60 R63 N64 P65 K66 I71 I73 R76 T3 K4 K56 R59 R62 N63 P64 K65 I70 I72 R75 PDBbind-CN: Kd=4.6nM
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0001216 DNA-binding transcription activator activity
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006310 DNA recombination
GO:0006351 DNA-templated transcription
GO:0006355 regulation of DNA-templated transcription
GO:0006417 regulation of translation
GO:0045893 positive regulation of DNA-templated transcription
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0009295 nucleoid
GO:0032993 protein-DNA complex
GO:1990177 IHF-DNA complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1owf, PDBe:1owf, PDBj:1owf
PDBsum1owf
PubMed12842466
UniProtP0A6X7|IHFA_ECOLI Integration host factor subunit alpha (Gene Name=ihfA)

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