Structure of PDB 1ow7 Chain A

Receptor sequence
>1ow7A (length=134) Species: 9606 (Homo sapiens) [Search protein sequence]
NLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLL
ATVDETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQE
YKKQMLTAAHALAVDAKNLLDVIDQARLKMLGQT
3D structure
PDB1ow7 Molecular Recognition of Paxillin LD Motifs by the Focal Adhesion Targeting Domain
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y925 I936 H1025 K1032 Y10 I21 H110 K117
Gene Ontology
Molecular Function
GO:0004713 protein tyrosine kinase activity
Biological Process
GO:0006468 protein phosphorylation
GO:0007172 signal complex assembly
Cellular Component
GO:0005925 focal adhesion

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1ow7, PDBe:1ow7, PDBj:1ow7
PDBsum1ow7
PubMed14527389
UniProtQ05397|FAK1_HUMAN Focal adhesion kinase 1 (Gene Name=PTK2)

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