Structure of PDB 1osb Chain A

Receptor sequence

>1osbA (length=287) Species: 562 (Escherichia coli) [Search protein sequence]

MLSHMVLTRQDIGRAASYYEDGADGDASEWQGKGAEELGLSGEVDSKRFR
ELLAGNIGEGHRIMRSATRQDSKERIGLDLTFSAPKSVSLQALVAGDAEI
IKAHDRAVARTLEQAEARAQARQKIQGKTRIETTGNLVIGKFRHETSRER
DPQLHTHAVILNMTKRSDGQWRALKNDEIVKATRYLGAVYNAELAHELQK
LGYQLRYGKDGNFDLAHIDRQQIEGFSKRTEQIAEWYAARGLDPNSVSLE
QKQAAKVLSRAKKTSVDREALRAEWQATAKELGIDFS

3D structure

PDB

1osb Recognition and processing of the origin of transfer DNA by conjugative relaxase TrwC.

Chain

Resolution

2.65 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	A	M1 S3 H4 S72 A73 T74 R75 Q76 D77 K79 R81 S89 A90 P91 K92 R128 K130 Q132 T152 R154 Q159 H161 H163 R172 R178 A179 N182 D183 K215 N218 R226 S233 R235 T236 I239 L255 K258 K262 R266	M1 S3 H4 S66 A67 T68 R69 Q70 D71 K73 R75 S83 A84 P85 K86 R122 K124 Q126 T146 R148 Q153 H155 H157 R166 R172 A173 N176 D177 K209 N212 R220 S227 R229 T230 I233 L249 K252 K256 R260	PDBbind-CN: Kd=70nM

External links

PDB	RCSB:1osb, PDBe:1osb, PDBj:1osb
PDBsum	1osb
PubMed	14625590
UniProt	Q47673

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