Structure of PDB 1oqh Chain A

Receptor sequence
>1oqhA (length=329) Species: 9606 (Homo sapiens) [Search protein sequence]
DKTVRWCAVSEHEATKCQSFRDHMKSVIPSDGPSVACVKKASYLDCIRAI
AANEADAVTLDAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVK
KDSGFQMNQLRGKKSCHTGLGASAGWNIPIGLLYCDLPEPRKPLEKAVAN
FFSGSCAPCADGTDFPQLCQLCPGCGCSTLNQYFGYSGAFKCLKDGAGDV
AFVKHSTIFENLANKADRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVV
ARSMGGKEDLIWELLNQAQEHFGKDKSKEFQLFSSPHGKDLLFKDSAHGF
LKVPPRMDAKMYLGYEYVTAIRNLREGTC
3D structure
PDB1oqh Structural and functional consequences of binding site mutations in transferrin: crystal structures of the Asp63Glu and Arg124Ala mutants of the N-lobe of human transferrin
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CO3 A D63 T120 A124 S125 A126 Y188 D61 T118 A122 S123 A124 Y186
BS02 FE A D63 Y95 Y188 H249 D61 Y93 Y186 H247
Gene Ontology
Cellular Component
GO:0005576 extracellular region

View graph for
Cellular Component
External links
PDB RCSB:1oqh, PDBe:1oqh, PDBj:1oqh
PDBsum1oqh
PubMed12795604
UniProtP02787|TRFE_HUMAN Serotransferrin (Gene Name=TF)

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