Structure of PDB 1ooa Chain A

Receptor sequence
>1ooaA (length=313) Species: 10090 (Mus musculus) [Search protein sequence]
GGPYLQILEQPKQRGFRFRYVCEGPSHGGLPGASSEKNKKSYPQVKICNY
VGPAKVIVQLVTNGKNIHLHAHSLVGKHCEDGVCTVTAGPKDMVVGFANL
GILHVTKKKVFETLEARMTEACIRGYNPGLLVHSDLAYLQAEGGGDRQLT
DREKEIIRQAAVQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAI
YDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEE
NGGVWEGFGDFSPTDVHRQFAIVFKTPKYKDVNITKPASVFVQLRRKSDL
ETSEPKPFLYYPE
3D structure
PDB1ooa Crystal structure of NF-kappaB (p50)2 complexed to a high-affinity RNA aptamer.
ChainA
Resolution2.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A R56 Y57 C59 E60 P62 S63 H64 K77 T143 K144 K145 K241 A242 P243 K249 R19 Y20 C22 E23 P25 S26 H27 K40 T106 K107 K108 K204 A205 P206 K212
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1ooa, PDBe:1ooa, PDBj:1ooa
PDBsum1ooa
PubMed12886018
UniProtP25799|NFKB1_MOUSE Nuclear factor NF-kappa-B p105 subunit (Gene Name=Nfkb1)

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