Structure of PDB 1oj6 Chain A

Receptor sequence
>1oj6A (length=147) Species: 9606 (Homo sapiens) [Search protein sequence]
RPEPELIRQSWRAVSRSPLEHGTVLFARLFALEPDLLPLFQYNGRQFSSP
EDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLASLGRKHRAVGVK
LSSFSTVGESLLYMLEKSLGPAFTPATRAAWSQLYGAVVQAMSRGWD
3D structure
PDB1oj6 Human Brain Neuroglobin Structure Reveals a Distinct Mode of Controlling Oxygen Affinity
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.7.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A H64 K67 V68 V71 L92 H96 F106 V109 H62 K65 V66 V69 L90 H94 F104 V107
BS02 HEM A T77 N78 T75 N76
Gene Ontology
Molecular Function
GO:0005092 GDP-dissociation inhibitor activity
GO:0005344 oxygen carrier activity
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0019825 oxygen binding
GO:0020037 heme binding
GO:0046872 metal ion binding
GO:0098809 nitrite reductase activity
Biological Process
GO:0001666 response to hypoxia
GO:0015671 oxygen transport
GO:0071456 cellular response to hypoxia
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:1oj6, PDBe:1oj6, PDBj:1oj6
PDBsum1oj6
PubMed12962627
UniProtQ9NPG2|NGB_HUMAN Neuroglobin (Gene Name=NGB)

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