Structure of PDB 1ohe Chain A

Receptor sequence
>1oheA (length=338) Species: 9606 (Homo sapiens) [Search protein sequence]
RDPQDDVYLDITDRLCFAILYSRPKSASNVHYFSIDNELEYENFYADFGP
LNLAMVYRYCCKINKKLKSITMLRKKIVHFTGSDQRKQANAAFLVGCYMV
IYLGRTPEEAYRILIFGETSYIPFRDAAYGSCNFYITLLDCFHAVKKAMQ
YGFLNFNSFNLDEYEHYEKAENGDLNWIIPDRFIAFCGPHSRARLESGYH
QHSPETYIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTP
TDAIVKEFLDICENAEGAIAVHSKAGLGRTGTLIACYIMKHYRMTAAETI
AWVRICRPGSVIGPQQQFLVMKQTNLWLEGDYFRQKLK
3D structure
PDB1ohe The Structure of the Cell Cycle Protein Cdc14 Reveals a Proline-Directed Protein Phosphatase
ChainA
Resolution2.2 Å
3D
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Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
3.1.3.48: protein-tyrosine-phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A D287 G288 S314 K315 A316 L318 G319 R320 I353 K379 D246 G247 S273 K274 A275 L277 G278 R279 I312 K338
Gene Ontology
Biological Process
GO:0006470 protein dephosphorylation
GO:0016311 dephosphorylation

View graph for
Biological Process
External links
PDB RCSB:1ohe, PDBe:1ohe, PDBj:1ohe
PDBsum1ohe
PubMed12853468
UniProtO60729|CC14B_HUMAN Dual specificity protein phosphatase CDC14B (Gene Name=CDC14B)

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