Structure of PDB 1ogz Chain A

Receptor sequence
>1ogzA (length=125) Species: 285 (Comamonas testosteroni) [Search protein sequence]
MNTPEHMTAVVQRYVAALNAGDLDGIVALFADDATVEDAVGSEPRSGTAA
IREFYANSLKLPLAVELTQEVRAVANEAAFAFIVSFEYQGRKTVVAPIDH
FRFNGAGKVVSMRALFGEKNIHAGA
3D structure
PDB1ogz The Conserved Cis-Pro39 Residue Plays a Crucial Role in the Proper Positioning of the Catalytic Base Asp38 in Ketosteroid Isomerase from Comamonas Testosteroni.
ChainA
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y14 D38 A96 D99
Catalytic site (residue number reindexed from 1) Y14 D38 A96 D99
Enzyme Commision number 5.3.3.1: steroid Delta-isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 EQU A Y14 S58 L63 F86 D99 F116 Y14 S58 L63 F86 D99 F116 MOAD: Kd=1.4uM
PDBbind-CN: -logKd/Ki=5.85,Kd=1.4uM
Gene Ontology
Molecular Function
GO:0004769 steroid delta-isomerase activity
GO:0016853 isomerase activity
Biological Process
GO:0008202 steroid metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1ogz, PDBe:1ogz, PDBj:1ogz
PDBsum1ogz
PubMed12852789
UniProtP00947|SDIS_COMTE Steroid Delta-isomerase (Gene Name=ksi)

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