Structure of PDB 1ogx Chain A

Receptor sequence
>1ogxA (length=126) Species: 303 (Pseudomonas putida) [Search protein sequence]
NLPTAQEVQGLMARYIELVDVGDIEAIVQMYADDATVENPFGQPPIHGRE
QIAAFYRQGLGGGKVRACLTGPVRASHNGCGAMPFRVEMVWNGQPCALDV
IDVMRFDEHGRIQTMQAYWSEVNLSV
3D structure
PDB1ogx Detection of Large Pka Perturbation of an Inhibitor and a Catalytic Group at an Enzyme Active Site, a Mechanistic Basis for Catalytic Power of Many Enzymes
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.3.3.1: steroid Delta-isomerase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 EQU A Y16 N40 V88 M90 D103 W120 Y15 N39 V87 M89 D102 W119 MOAD: Kd=0.81uM
Gene Ontology
Molecular Function
GO:0004769 steroid delta-isomerase activity
GO:0016853 isomerase activity
Biological Process
GO:0008202 steroid metabolic process

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:1ogx, PDBe:1ogx, PDBj:1ogx
PDBsum1ogx
PubMed11007792
UniProtP07445|SDIS_PSEPU Steroid Delta-isomerase (Gene Name=ksi)

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