Structure of PDB 1og4 Chain A

Receptor sequence
>1og4A (length=223) Species: 10116 (Rattus norvegicus) [Search protein sequence]
PLMLDTAPNAFDDQYEGCVNKMEEKAPLLLQEDFNMNAKLKVAWEEAKKR
WNNIKPSRSYPKGFNDFHGTALVAYTGSIAVDFNRAVREFKENPGQFHYK
AFHYYLTRALQLLSNGDCHSVYRGTKTRFHYTGAGSVRFGQFTSSSLSKK
VAQSQEFFSDHGTLFIIKTCLGVYIKEFSFRPDQEAVLIPGYEVYQKVRT
QGYNEIFLDSPKRKKSNYNCLYS
3D structure
PDB1og4 Substrate Binding and Catalysis of Ecto-Adp-Ribosyltransferase 2.2 From Rat
ChainA
Resolution2.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S147 E159 R184 A189
Catalytic site (residue number reindexed from 1) S144 E156 R181 A186
Enzyme Commision number 2.4.2.31: NAD(+)--protein-arginine ADP-ribosyltransferase.
3.2.2.5: NAD(+) glycohydrolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAI A L5 N87 R91 R126 G127 F132 Q144 S147 S148 F160 L2 N84 R88 R123 G124 F129 Q141 S144 S145 F157
Gene Ontology
Molecular Function
GO:0106274 NAD+-protein-arginine ADP-ribosyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:1og4, PDBe:1og4, PDBj:1og4
PDBsum1og4
PubMed12939142
UniProtP20974|NAR2B_RAT T-cell ecto-ADP-ribosyltransferase 2 (Gene Name=Art2b)

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