Structure of PDB 1og1 Chain A

Receptor sequence
>1og1A (length=223) Species: 10116 (Rattus norvegicus) [Search protein sequence]
PLMLDTAPNAFDDQYEGCVNKMEEKAPLLLQEDFNMNAKLKVAWEEAKKR
WNNIKPSRSYPKGFNDFHGTALVAYTGSIAVDFNRAVREFKENPGQFHYK
AFHYYLTRALQLLSNGDCHSVYRGTKTRFHYTGAGSVRFGQFTSSSLSKK
VAQSQEFFSDHGTLFIIKTCLGVYIKEFSFRPDQEEVLIPGYEVYQKVRT
QGYNEIFLDSPKRKKSNYNCLYS
3D structure
PDB1og1 Substrate Binding and Catalysis of Ecto-Adp-Ribosyltransferase 2.2 From Rat
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S147 E159 R184 E189
Catalytic site (residue number reindexed from 1) S144 E156 R181 E186
Enzyme Commision number 2.4.2.31: NAD(+)--protein-arginine ADP-ribosyltransferase.
3.2.2.5: NAD(+) glycohydrolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TAD A L5 N87 R91 R126 G127 Q144 S147 S148 F160 E189 L2 N84 R88 R123 G124 Q141 S144 S145 F157 E186
Gene Ontology
Molecular Function
GO:0106274 NAD+-protein-arginine ADP-ribosyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:1og1, PDBe:1og1, PDBj:1og1
PDBsum1og1
PubMed12939142
UniProtP20974|NAR2B_RAT T-cell ecto-ADP-ribosyltransferase 2 (Gene Name=Art2b)

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