Structure of PDB 1of2 Chain A

Receptor sequence
>1of2A (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFHTSVSRPGRGEPRFITVGYVDDTLFVRFDSDAASPREEPRAP
WIEQEGPEYWDRETQICKAKAQTDREDLRTLLRYYNQSEAGSHTLQNMYG
CDVGPDGRLLRGYHQHAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQLRAYLEGECVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
3D structure
PDB1of2 Dual, Hla-B27 Subtype-Dependent Conformation of a Self-Peptide
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 H9 T24 E45 R62 E63 Q65 I66 C67 T73 E76 D77 L81 Y84 Y99 T143 K146 W147 V152 Q155 L156 Y159 E163 W167 Y171 Y7 H9 T24 E45 R62 E63 Q65 I66 C67 T73 E76 D77 L81 Y84 Y99 T143 K146 W147 V152 Q155 L156 Y159 E163 W167 Y171
External links
PDB RCSB:1of2, PDBe:1of2, PDBj:1of2
PDBsum1of2
PubMed14734527
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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