Structure of PDB 1oe8 Chain A

Receptor sequence
>1oe8A (length=204) Species: 6185 (Schistosoma haematobium) [Search protein sequence]
DHIKVIYFNGRGRAESIRMTLVAAGVNYEDERISFQDWPKIKPTIPGGRL
PAVKITDNHGHVKWMVESLAIARYMAKKHHMMGGTEEEYYNVEKLIGQAE
DLEHEYYKTLMKPEEEKQKIIKEILNGKVPVLLDIICESLKASTGKLAVG
DKVTLADLVLIAVIDHVTDLDKEFLTGKYPEIHKHRENLLASSPRLAKYL
SDRA
3D structure
PDB1oe8 Crystal Structure of the 28 kDa Glutathione S-Transferase from Schistosoma Haematobium
ChainA
Resolution1.65 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y10 R16 R21
Catalytic site (residue number reindexed from 1) Y7 R13 R18
Enzyme Commision number 2.5.1.18: glutathione transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSH A R16 W41 K45 R52 L53 E70 S71 R13 W38 K42 R49 L50 E67 S68 MOAD: Kd=9uM
PDBbind-CN: -logKd/Ki=5.52,Kd=3uM
Gene Ontology
Molecular Function
GO:0004364 glutathione transferase activity
GO:0016740 transferase activity
Biological Process
GO:0006749 glutathione metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1oe8, PDBe:1oe8, PDBj:1oe8
PDBsum1oe8
PubMed12939136
UniProtP30114|GST28_SCHBO Glutathione S-transferase class-mu 28 kDa isozyme

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