Structure of PDB 1oe7 Chain A

Receptor sequence
>1oe7A (length=204) Species: 6185 (Schistosoma haematobium) [Search protein sequence]
DHIKVIYFNGRGRAESIRMTLVAAGVNYEDERISFQDWPKIKPTIPGGRL
PAVKITDNHGHVKWMVESLAIARYMAKKHHMMGGTEEEYYNVEKLIGQAE
DLEHEYYKTLMKPEEEKQKIIKEILNGKVPVLLDIICESLKASTGKLAVG
DKVTLADLVLIAVIDHVTDLDKEFLTGKYPEIHKHRENLLASSPRLAKYL
SDRA
3D structure
PDB1oe7 Crystal Structure of the 28 kDa Glutathione S-Transferase from Schistosoma Haematobium
ChainA
Resolution1.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y10 R16 R21
Catalytic site (residue number reindexed from 1) Y7 R13 R18
Enzyme Commision number 2.5.1.18: glutathione transferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GSH A Y10 F11 R16 W41 K45 R52 L53 E70 S71 Y7 F8 R13 W38 K42 R49 L50 E67 S68 MOAD: Kd=9uM
PDBbind-CN: -logKd/Ki=5.52,Kd=3uM
Gene Ontology
Molecular Function
GO:0004364 glutathione transferase activity
GO:0016740 transferase activity
Biological Process
GO:0006749 glutathione metabolic process

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Molecular Function

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Biological Process
External links
PDB RCSB:1oe7, PDBe:1oe7, PDBj:1oe7
PDBsum1oe7
PubMed12939136
UniProtP30114|GST28_SCHBO Glutathione S-transferase class-mu 28 kDa isozyme

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