Structure of PDB 1oe6 Chain A

Receptor sequence
>1oe6A (length=244) Species: 8355 (Xenopus laevis) [Search protein sequence]
SPADSFLKVELELNLKLSNLVFQDPVQYVYNPLVYAWAPHENYVQTYCKS
KKEVLFLGMNPGPFGMAQTGVPFGEVNHVRDWLQIEGPVSKPEVEHPKRR
IRGFECPQSEVSGARFWSLFKSLCGQPETFFKHCFVHNHCPLIFMNHSGK
NLTPTDLPKAQRDTLLEICDEALCQAVRVLGVKLVIGVGRFSEQRARKAL
MAEGIDVTVKGIMHPSPRNPQANKGWEGIVRGQLLELGVLSLLT
3D structure
PDB1oe6 Structure and Specificity of the Vertebrate Anti-Mutator Uracil-DNA Glycosylase Smug1
ChainA
Resolution2.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R226 R254 Q257 R190 R218 Q221
BS02 dna A K195 R198 P256 K159 R162 P220
BS03 HMU A N96 G98 G101 M102 F109 E146 N174 H250 N60 G62 G65 M66 F73 E110 N138 H214
BS04 HMU A E146 V147 E110 V111
Gene Ontology
Molecular Function
GO:0017065 single-strand selective uracil DNA N-glycosylase activity
Biological Process
GO:0006284 base-excision repair

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Molecular Function
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Biological Process
External links
PDB RCSB:1oe6, PDBe:1oe6, PDBj:1oe6
PDBsum1oe6
PubMed12820976
UniProtQ9YGN6|SMUG1_XENLA Single-strand selective monofunctional uracil DNA glycosylase (Gene Name=smug1)

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