Structure of PDB 1oc7 Chain A

Receptor sequence
>1oc7A (length=364) Species: 34413 (Humicola insolens) [Search protein sequence]
APYNGNPFEGVQLWANNYYRSEVHTLAIPQITDPALRAAASAVAEVPSFQ
WLDRNVTVDTLLVQTLSEIREANQAGANPQYAAQIVVYDLPDRDCAAAAS
NGEWAIANNGVNNYKAYINRIREILISFSDVRTILVIEPDSLANMVTNMN
VPKCSGAASTYRELTIYALKQLDLPHVAMYMDAGHAGWLGWPANIQPAAE
LFAKIYEDAGKPRAVRGLATNVANYNAWSVSSPPPYTSPNPNYDEKHYIE
AFRPLLEARGFPAQFIVDQGRSGKQPTGQKEWGHWCNAIGTGFGMRPTAN
TGHQYVDAFVWVKPGGECNGTSDTTAARYDYHCGLEDALKPAPEAGQWFN
EYFIQLLRNANPPF
3D structure
PDB1oc7 Structural Basis for Ligand Binding and Processivity in Cellobiohydrolase Cel6A from Humicola Insolens
ChainA
Resolution1.11 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y174 R179 D180 S186 D226 N405
Catalytic site (residue number reindexed from 1) Y88 R93 D94 S100 D140 N319
Enzyme Commision number 3.2.1.91: cellulose 1,4-beta-cellobiosidase (non-reducing end).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SGC A N234 H271 W274 N148 H185 W188
BS02 SGC A A183 W371 A97 W285
BS03 BGC A W137 Y174 N187 A309 W51 Y88 N101 A223
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0030245 cellulose catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1oc7, PDBe:1oc7, PDBj:1oc7
PDBsum1oc7
PubMed12842048
UniProtQ9C1S9|GUX6_HUMIN Exoglucanase-6A (Gene Name=cel6A)

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