Structure of PDB 1obg Chain A

Receptor sequence
>1obgA (length=305) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
SITKTELDGILPLVARGKVRDIYEVDAGTLLFVATDRISAYDVIMENSIP
EKGILLTKLSEFWFKFLSNDVRNHLVDIAPGKTIFDYLPAKLSEPKYKTQ
LEDRSLLVHKHKLIPLEVIVRGYITGSAWKEYVKTGTVHGLKQPQGLKES
QEFPEPIFTPSTKAEQGEHDENISPAQAAELVGEDLSRRVAELAVKLYSK
CKDYAKEKGIIIADTKFEFGIDEKTNEIILVDEVLTPDSSRFWNGASYKV
GESQDSYDKQFLRDWLTANKLNGVNGVKMPQDIVDRTRAKYIEAYETLTG
SKWSH
3D structure
PDB1obg The Structure of Saicar Synthase: An Enzyme in the De Novo Pathway of Purine Nucleotide Biosynthesis
ChainA
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.2.6: phosphoribosylaminoimidazolesuccinocarboxamide synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP A R21 I23 F33 H75 K111 H112 K164 E219 V232 D233 R20 I22 F32 H74 K110 H111 K163 E218 V231 D232
BS02 AMP A E62 V77 I79 I85 L107 L108 E61 V76 I78 I84 L106 L107
BS03 MG A P238 D239 D259 Y292 P237 D238 D258 Y291
Gene Ontology
Molecular Function
GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016874 ligase activity
Biological Process
GO:0006164 purine nucleotide biosynthetic process
GO:0006189 'de novo' IMP biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1obg, PDBe:1obg, PDBj:1obg
PDBsum1obg
PubMed
UniProtP27616|PUR7_YEAST Phosphoribosylaminoimidazole-succinocarboxamide synthase (Gene Name=ADE1)

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