Structure of PDB 1o9k Chain A

Receptor sequence
>1o9kA (length=194) Species: 9606 (Homo sapiens) [Search protein sequence]
MNTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKRVKDIGYIFKE
KFAKAVGQGCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLN
DNIFHMSLLACALEVVMATYSRSSGTDLSFPWILNVLNLKAFDFYKVIES
FIKAEGNLTREMIKHLERCEHRIMESLAWLSDSPLFDLIKQSKD
3D structure
PDB1o9k Crystal Structure of the Retinoblastoma Tumor Suppressor Protein Bound to E2F and the Molecular Basis of its Regulation
ChainA
Resolution2.6 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A E464 R467 L468 F482 K530 E533 S534 I536 K537 E554 E86 R89 L90 F104 K146 E149 S150 I152 K153 E170
Gene Ontology
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1o9k, PDBe:1o9k, PDBj:1o9k
PDBsum1o9k
PubMed12598654
UniProtP06400|RB_HUMAN Retinoblastoma-associated protein (Gene Name=RB1)

[Back to BioLiP]