Structure of PDB 1o5k Chain A

Receptor sequence
>1o5kA (length=295) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence]
HMFRGVGTAIVTPFKNGELDLESYERLVRYQLENGVNALIVLGTTGESPT
VNEDEREKLVSRTLEIVDGKIPVIVGAGTNSTEKTLKLVKQAEKLGANGV
LVVTPYYNKPTQEGLYQHYKYISERTDLGIVVYNVPGRTGVNVLPETAAR
IAADLKNVVGIKEANPDIDQIDRTVSLTKQARSDFMVWSGNDDRTFYLLC
AGGDGVISVVSNVAPKQMVELCAEYFSGNLEKSREVHRKLRPLMKALFVE
TNPIPVKAALNLMGFIENELRLPLVPASEKTVELLRNVLKESGLL
3D structure
PDB1o5k Crystal structure of Dihydrodipicolinate synthase (TM1521) from Thermotoga maritima at 1.80 A resolution
ChainA
Resolution1.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) T43 Y106 Y132 R137 K161 I206
Catalytic site (residue number reindexed from 1) T44 Y107 Y133 R138 K162 I207
Enzyme Commision number 4.3.3.7: 4-hydroxy-tetrahydrodipicolinate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A E64 D67 E65 D68
Gene Ontology
Molecular Function
GO:0008840 4-hydroxy-tetrahydrodipicolinate synthase activity
GO:0016829 lyase activity
Biological Process
GO:0009085 lysine biosynthetic process
GO:0009089 lysine biosynthetic process via diaminopimelate
GO:0019877 diaminopimelate biosynthetic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:1o5k, PDBe:1o5k, PDBj:1o5k
PDBsum1o5k
PubMed
UniProtQ9X1K9|DAPA_THEMA 4-hydroxy-tetrahydrodipicolinate synthase (Gene Name=dapA)

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