Structure of PDB 1o4x Chain A

Receptor sequence
>1o4xA (length=129) Species: 9606 (Homo sapiens) [Search protein sequence]
EEPSDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRF
EALNLSFKNMAKLKPLLEKWLNDAESIETNIRVALEKSFLENQKPTSEEI
TMIADQLNMEKEVIRVWFCNRRQKEKRIN
3D structure
PDB1o4x Molecular basis for synergistic transcriptional activation by Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1.Sox2.Hoxb1-DNA ternary transcription factor complex.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A Q48 T49 S52 R53 I111 W151 N154 K158 Q44 T45 S48 R49 I77 W117 N120 K124
BS02 dna A D45 F46 S47 T49 K62 N63 Q157 D41 F42 S43 T45 K58 N59 Q123
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1o4x, PDBe:1o4x, PDBj:1o4x
PDBsum1o4x
PubMed14559893
UniProtP14859|PO2F1_HUMAN POU domain, class 2, transcription factor 1 (Gene Name=POU2F1)

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