Structure of PDB 1o2f Chain A

Receptor sequence
>1o2fA (length=150) Species: 562 (Escherichia coli) [Search protein sequence]
TIEIIAPLSGEIVNIEDVPDVVFAEKIVGDGIAIKPTGNKMVAPVDGTIG
KIFETNHAFSIESDSGVELFVHFGIDTVELKGEGFKRIAEEGQRVKVGDT
VIEFDLPLLEEKAKSTLTPVVISNMDEIKELIKLSGSVTVGETPVIRIKK
3D structure
PDB1o2f Solution Structure of the Phosphoryl Transfer Complex between the Signal-transducing Protein IIAGlucose and the Cytoplasmic Domain of the Glucose Transporter IICBGlucose of the Escherichia coli Glucose Phosphotransferase System.
ChainA
ResolutionN/A
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) T73 H75 H90
Catalytic site (residue number reindexed from 1) T55 H57 H72
Enzyme Commision number 2.7.1.69: Transferred entry: 2.7.1.191, 2.7.1.192, 2.7.1.193, 2.7.1.194, 2.7.1.195, 2.7.1.196, 2.7.1.197, 2.7.1.198, 2.7.1.199, 2.7.1.200, 2.7.1.201, 2.7.1.202, 2.7.1.203, 2.7.1.204, 2.7.1.205, 2.7.1.206, 2.7.1.207 and 2.7.1.208.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PO3 A H90 D94 H72 D76
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0016301 kinase activity
GO:0046872 metal ion binding
Biological Process
GO:0009401 phosphoenolpyruvate-dependent sugar phosphotransferase system
GO:0016310 phosphorylation
GO:0034763 negative regulation of transmembrane transport
GO:0043610 regulation of carbohydrate utilization
GO:0045912 negative regulation of carbohydrate metabolic process
GO:1902344 negative regulation of maltose transport
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0009898 cytoplasmic side of plasma membrane
GO:0016020 membrane
GO:1902495 transmembrane transporter complex
GO:1990154 enzyme IIA-maltose transporter complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1o2f, PDBe:1o2f, PDBj:1o2f
PDBsum1o2f
PubMed12716891
UniProtP69783|PTGA_ECOLI PTS system glucose-specific EIIA component (Gene Name=crr)

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