Structure of PDB 1nzi Chain A

Receptor sequence
>1nziA (length=155) Species: 9606 (Homo sapiens) [Search protein sequence]
EPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENC
AYDSVQIISEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEE
RFTGFAAYYVATDINECTDVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMK
NCGVN
3D structure
PDB1nzi X-ray structure of the Ca2+-binding interaction domain of C1s. Insights into the assembly of the C1 complex of complement
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.42: complement subcomponent C1s.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D116 I117 E119 N134 F135 G138 D113 I114 E116 N130 F131 G134
BS02 MG A E45 D53 D98 E45 D53 D95
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:1nzi, PDBe:1nzi, PDBj:1nzi
PDBsum1nzi
PubMed12788922
UniProtP09871|C1S_HUMAN Complement C1s subcomponent (Gene Name=C1S)

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