Structure of PDB 1nyt Chain A

Receptor sequence
>1nytA (length=271) Species: 562 (Escherichia coli) [Search protein sequence]
METYAVFGNPIAHSKSPFIHQQFAQQLNIEHPYGRVLAPINDFINTLNAF
FSAGGKGANVTVPFKEEAFARADELTERAALAGAVNTLMRLEDGRLLGDN
TDGVGLLSDLERLSFIRPGLRILLIGAGGASRGVLLPLLSLDCAVTITNR
TVSRAEELAKLFAHTGSIQALSMDELEGHEFDLIINATSSGISGDIPAIP
SSLIHPGIYCYDMFYQKGKTPFLAWCEQRGSKRNADGLGMLVAQAAHAFL
LWHGVLPDVEPVIKQLQEELS
3D structure
PDB1nyt Structures of shikimate dehydrogenase AroE and its Paralog YdiB. A common structural framework for different activities.
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.25: shikimate dehydrogenase (NADP(+)).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP A K65 D102 G128 G129 A130 N149 R150 T151 R154 T188 S189 S190 M213 G237 M240 L241 K65 D102 G128 G129 A130 N149 R150 T151 R154 T188 S189 S190 M213 G237 M240 L241
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004764 shikimate 3-dehydrogenase (NADP+) activity
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0050661 NADP binding
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009073 aromatic amino acid family biosynthetic process
GO:0009423 chorismate biosynthetic process
GO:0019632 shikimate metabolic process
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:1nyt, PDBe:1nyt, PDBj:1nyt
PDBsum1nyt
PubMed12637497
UniProtP15770|AROE_ECOLI Shikimate dehydrogenase (NADP(+)) (Gene Name=aroE)

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