Structure of PDB 1nwd Chain A

Receptor sequence

>1nwdA (length=148) Species: 8355 (Xenopus laevis)

ADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD
MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYI
SAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK

3D structure

• PDB: 1nwd Structural Basis for Simultaneous Binding of Two Carboxy-terminal Peptides of Plant Glutamate Decarboxylase to Calmodulin
• Chain: A
• Resolution: N/A

Enzymatic activity

• Catalytic site (original residue number in PDB): V35
• Catalytic site (residue number reindexed from 1): V35

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	M76 A88 M109 E114 L116 T117 E120 V121 M124	M76 A88 M109 E114 L116 T117 E120 V121 M124
BS02	peptide	A	F19 L39 E47 D50 M51 M71 E127 M145 A147 K148	F19 L39 E47 D50 M51 M71 E127 M145 A147 K148
BS03	CA	A	D22 D24 T26 E31	D22 D24 T26 E31
BS04	CA	A	N60 T62 D64 E67	N60 T62 D64 E67
BS05	CA	A	D93 N97 Y99 I100 S101 E104 Q135	D93 N97 Y99 I100 S101 E104 Q135
BS06	CA	A	D129 D131 G132 D133 Q135 E140	D129 D131 G132 D133 Q135 E140

Gene Ontology

Molecular Function

• GO:0005102 signaling receptor binding
• GO:0005509 calcium ion binding
• GO:0030234 enzyme regulator activity
• GO:0046872 metal ion binding

External links

• PDB: RCSB:1nwd, PDBe:1nwd, PDBj:1nwd
• PDBsum: 1nwd
• PubMed: 12684008
• UniProt: P0DP33|CALM1_XENLA Calmodulin-1 (Gene Name=calm1)