Structure of PDB 1nst Chain A

Receptor sequence
>1nstA (length=282) Species: 9606 (Homo sapiens) [Search protein sequence]
DPLWQDPCCDRFPKLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEE
IQFFNGHNYHKGIDWYMEFFPISDFYFEKSANYFDSEVAPRRAAALLPKA
KVLTILINPADRAYSWYQHQRAHDDPVALKYTFHEVITAGSDASSKLRAL
QNRCLVPGWYATHIERWLSAYHANQILVLDGKLLRTEPAKVMDMVQKFLG
VTNTIDYHKTLAFDPKKGFWCQLLEGGKTKCLGKSKGRKYPEMDLDSRAF
LKDYYRDHNIELSKLLYKMGQTLPTWLREDLQ
3D structure
PDB1nst Crystal structure of the sulfotransferase domain of human heparan sulfate N-deacetylase/ N-sulfotransferase 1.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.8.2.8: [heparan sulfate]-glucosamine N-sulfotransferase.
3.5.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A3P A K614 G616 T617 T618 A619 S712 F816 L829 K833 G834 R835 Y837 K22 G24 T25 T26 A27 S115 F219 L232 K236 G237 R238 Y240
Gene Ontology
Molecular Function
GO:0008146 sulfotransferase activity

View graph for
Molecular Function
External links
PDB RCSB:1nst, PDBe:1nst, PDBj:1nst
PDBsum1nst
PubMed10196134
UniProtP52848|NDST1_HUMAN Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (Gene Name=NDST1)

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