Structure of PDB 1nqf Chain A

Receptor sequence
>1nqfA (length=544) Species: 562 (Escherichia coli) [Search protein sequence]
TLVVTANRFEQPRSTVLAPTTVVTRQDIDRWQSTSVNDVLRRLPGVDITQ
NGGSGQLSSIFIRGTNASHVLVLIDGVRLNLAGVSGSADLSQFPIALVQR
VEYIRGPRSAVYGSDAIGGVVNIITTRDEPGTEISAGWGSNSYQNYDVST
QQQLGDKTRVTLLGDYAHTHGFLSKTLYGALEHNFTDAWSGFVRGYGYDN
RTNDTRKLYSQSWDAGLRYNGELIKSQLITSYSHSKDYNYATLDEMKQYT
VQWANNVIVGHGSIGAGVDMQMQMTTPGTGDGYDQRNTGIYLTGLQQVGD
FTFEGAARSDDNSQFGRHGTWQTSAGWEFIEGYRFIASYGTSYKAPNLGQ
LYGFYGNPNLDPEKSKQWEGAFEGLTAGVNWRISGYRNDVSDLIDYDDHT
LKYYNEGKARIKGVEATANFDTGPLTHTVSYDYVDARNAITDTPLLRRAK
QQVKYQLDWQLYDFDMGMTMQYLGTRYDKDYSSYPYQTVKMGGVSLWDLA
VAYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF
3D structure
PDB1nqf Substrate-induced transmembrane signaling in the cobalamin transporter BtuB
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 C8E A R358 S359 R367 G369 T370 R308 S309 R317 G319 T320
BS02 C8E A F379 Y383 F422 F329 Y333 F372
BS03 C8E A A466 T467 Y481 A416 T417 Y431
BS04 C8E A I311 L342 G344 T373 I264 L292 G294 T323
BS05 C8E A I433 S434 G435 Y436 K462 G463 V464 I383 S384 G385 Y386 K412 G413 V414
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0015288 porin activity
GO:0015420 ABC-type vitamin B12 transporter activity
GO:0019904 protein domain specific binding
GO:0046872 metal ion binding
GO:0090482 vitamin transmembrane transporter activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0015889 cobalamin transport
GO:0034220 monoatomic ion transmembrane transport
GO:0035461 vitamin transmembrane transport
Cellular Component
GO:0009279 cell outer membrane
GO:0016020 membrane
GO:0046930 pore complex
GO:1902495 transmembrane transporter complex

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Cellular Component
External links
PDB RCSB:1nqf, PDBe:1nqf, PDBj:1nqf
PDBsum1nqf
PubMed12652322
UniProtP06129|BTUB_ECOLI Vitamin B12 transporter BtuB (Gene Name=btuB)

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