Structure of PDB 1nqe Chain A

Receptor sequence
>1nqeA (length=549) Species: 562 (Escherichia coli) [Search protein sequence]
DTLVVTANRFEQPRSTVLAPTTVVTRQDIDRWQSTSVNDVLRRLPGVDIT
QNGGSGQLSSIFIRGTNASHVLVLIDGVRLNLAGVSGSADLSQFPIALVQ
RVEYIRGPRSAVYGSDAIGGVVNIITTRDEPGTEISAGWGSNSYQNYDVS
TQQQLGDKTRVTLLGDYAHTHGGFLSKTLYGALEHNFTDAWSGFVRGYGY
DNRTNDTRKLYSQSWDAGLRYNGELIKSQLITSYSHSKDYNYATLDEMKQ
YTVQWANNVIVGHGSIGAGVDWQKQTTTPGTGYVEDGYDQRNTGIYLTGL
QQVGDFTFEGAARSDDNSQFGRHGTWQTSAGWEFIEGYRFIASYGTSYKA
PNLGQLYGFYGNPNLDPEKSKQWEGAFEGLTAGVNWRISGYRNDVSDLID
YDDHTLKYYNEGKARIKGVEATANFDTGPLTHTVSYDYVDARNAITDTPL
LRRAKQQVKYQLDWQLYDFDWGITYQYLGTRYDKDYSSYPYQTVKMGGVS
LWDLAVAYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF
3D structure
PDB1nqe Substrate-induced transmembrane signaling in the cobalamin transporter BtuB
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 C8E A A357 R358 S359 G369 T370 A312 R313 S314 G324 T325
BS02 C8E A Y383 F422 Y338 F377
BS03 C8E A G344 G355 A356 T373 G299 G310 A311 T328
BS04 C8E A Y436 K462 V464 Y391 K417 V419
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0015288 porin activity
GO:0015420 ABC-type vitamin B12 transporter activity
GO:0019904 protein domain specific binding
GO:0046872 metal ion binding
GO:0090482 vitamin transmembrane transporter activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0015889 cobalamin transport
GO:0034220 monoatomic ion transmembrane transport
GO:0035461 vitamin transmembrane transport
Cellular Component
GO:0009279 cell outer membrane
GO:0016020 membrane
GO:0046930 pore complex
GO:1902495 transmembrane transporter complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1nqe, PDBe:1nqe, PDBj:1nqe
PDBsum1nqe
PubMed12652322
UniProtP06129|BTUB_ECOLI Vitamin B12 transporter BtuB (Gene Name=btuB)

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