Structure of PDB 1nm1 Chain A

Receptor sequence
>1nm1A (length=364) Species: 44689 (Dictyostelium discoideum) [Search protein sequence]
DVQALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHTKDSYVGDEAQSK
RGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLN
PKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVSH
TVPIYEGYALPHAILRLDLAGRDLTDYMMKILTERGYSFTTTAEREIVRD
IKEKLAYVALDFEQEMATAASSSALEKSYELPDGQVITIGNERFRCPEAL
FQPSFLGMESAGIHETTYNSIMKCDVDIRKDLYGNVVLSGGTTMFPGIAD
RMNKELTALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKEE
YDESGPSIVHRKCF
3D structure
PDB1nm1 The Structure of Non-Vertebrate Actin: Implications For The ATP Hydrolytic Mechanism
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP A G13 S14 G15 K18 G156 D157 G182 R210 K213 E214 G301 G302 M305 F306 K336 G10 S11 G12 K15 G145 D146 G171 R199 K202 E203 G290 G291 M294 F295 K325
Gene Ontology
Molecular Function
GO:0005200 structural constituent of cytoskeleton
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0017022 myosin binding
Biological Process
GO:0000281 mitotic cytokinesis
GO:0000902 cell morphogenesis
GO:0001778 plasma membrane repair
GO:0006897 endocytosis
GO:0006909 phagocytosis
GO:0006935 chemotaxis
GO:0006972 hyperosmotic response
GO:0007010 cytoskeleton organization
GO:0016192 vesicle-mediated transport
GO:0042331 phototaxis
GO:0051591 response to cAMP
Cellular Component
GO:0001891 phagocytic cup
GO:0005737 cytoplasm
GO:0005811 lipid droplet
GO:0005856 cytoskeleton
GO:0005884 actin filament
GO:0005911 cell-cell junction
GO:0005938 cell cortex
GO:0015629 actin cytoskeleton
GO:0030027 lamellipodium
GO:0030139 endocytic vesicle
GO:0030864 cortical actin cytoskeleton
GO:0031143 pseudopodium
GO:0031252 cell leading edge
GO:0032009 early phagosome
GO:0032010 phagolysosome
GO:0045335 phagocytic vesicle
GO:0060187 cell pole
GO:0061836 intranuclear rod
GO:0061851 leading edge of lamellipodium
GO:0070685 macropinocytic cup

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1nm1, PDBe:1nm1, PDBj:1nm1
PDBsum1nm1
PubMed12732734
UniProtP07830|ACT1_DICDI Major actin (Gene Name=act1)

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