Structure of PDB 1nkt Chain A

Receptor sequence
>1nktA (length=836) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
DSPDLGTLVPRGSMADILSKLLRLGEGRMVKRLKKVADYVGTLSDDVEKL
TDAELRAKTDEFKRRLADQKNPETLDDLLPEAFAVAREAAWRVLDQRPFD
VQVMGAAALHLGNVAEMKTGEGKTLTCVLPAYLNALAGNGVHIVTVNDYL
AKRDSEWMGRVHRFLGLQVGVILATMTPDERRVAYNADITYGTNNEFGFD
YLRDNMAHSLDDLVQRGHHYAIVDEVDSILIDEARTPLIISGPADGASNW
YTEFARLAPLMEKDVHYEVDLRKRTVGVHEKGVEFVEDQLGIDNLYEAAN
SPLVSYLNNALKAKELFSRDKDYIVRDGEVLIVDEFTGRVLIGRRYNEGM
HQAIEAKEHVEIKAENQTLATITLQNYFRLYDKLAGMTGTAQTEAAELHE
IYKLGVVSIPTNMPMIREDQSDLIYKTEEAKYIAVVDDVAERYAKGQPVL
IGTTSVERSEYLSRQFTKRRIPHNVLNAKYHEQEATIIAVAGRRGGVTVA
TNMAGRGTDIVLGGNVDFLTDQRLRERGLDPVETPEEYEAAWHSELPIVK
EEASKEAKEVIEAGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYL
SLGDELMRRFNGAALETLLTRLNLPDDVPIEAKMVTRAIKSAQTQVEQQN
FEVRKNVLKYDEVMNQQRKVIYAERRRILEGENLKDQALDMVRDVITAYV
DGATGEGYAEDWDLDALWTALKTLYPVGITADSLTLLEALLKDAERAYAA
REAELEEIAGEGAMRQLERNVLLNVIDRKWREHLYEMDYLKEGIGLRAMA
QRDPLVEYQREGYDMFMAMLDGMKEESVGFLFNVTV
3D structure
PDB1nkt Crystal Structure of M. tuberculosis SecA, A Preprotein Translocating ATPase
ChainA
Resolution2.601 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 7.4.2.8: protein-secreting ATPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A Q80 R81 F83 Q86 G104 G106 K107 T108 D493 N499 D501 Q96 R97 F99 Q102 G120 G122 K123 T124 D509 N515 D517
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008564 protein-exporting ATPase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006605 protein targeting
GO:0006886 intracellular protein transport
GO:0015031 protein transport
GO:0017038 protein import
GO:0043952 protein transport by the Sec complex
GO:0065002 intracellular protein transmembrane transport
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall
GO:0016020 membrane
GO:0031522 cell envelope Sec protein transport complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1nkt, PDBe:1nkt, PDBj:1nkt
PDBsum1nkt
PubMed12606717
UniProtP9WGP5|SECA1_MYCTU Protein translocase subunit SecA 1 (Gene Name=secA1)

[Back to BioLiP]