Structure of PDB 1nkm Chain A

Receptor sequence
>1nkmA (length=220) Species: 10359 (Human betaherpesvirus 5) [Search protein sequence]
DEQQSQAVAPVYVGGFLARYDQSPDEAELLLPRDVVEHWLHAQALPLNIN
HDDTAVVGHVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSRGPV
SPLQPDKVVEFLSGSYAGLSLSSRRTTPFKHVALCSVGRRRGTLAVYGRD
PEWVTQRFPDLTAADRDGLRAQWQGDPFRSDSYGLLGNSVDALYIRERLP
KLRYDKQLVGVTERESYVKA
3D structure
PDB1nkm Structural and Biochemical Studies of Inhibitor Binding to Human Cytomegalovirus Protease
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.97: assemblin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 0FP A N62 H63 S132 S134 S135 R136 K156 C161 G164 R165 I231 N50 H51 S120 S122 S123 R124 K130 C135 G138 R139 I195 PDBbind-CN: -logKd/Ki=7.30,IC50<0.05uM
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1nkm, PDBe:1nkm, PDBj:1nkm
PDBsum1nkm
PubMed12549906
UniProtP16753|SCAF_HCMVA Capsid scaffolding protein (Gene Name=UL80)

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