Structure of PDB 1nju Chain A

Receptor sequence
>1njuA (length=230) Species: 10359 (Human betaherpesvirus 5) [Search protein sequence]
DEQQSQAVAPVYVGGFLARYDQSPDEAELLLPRDVVEHWLHAQLSVALPL
NINHDDTAVVGHVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSR
GPVSPLQPDKVVEFLSGSYAGLSLSSRRCDDVEQTTPFKHVALCSVGRRR
GTLAVYGRDPEWVTQRFPDLTAADRDGLRAQWQSGDPFRSDSYGLLGNSV
DALYIRERLPKLRYDKQLVGVTERESYVKA
3D structure
PDB1nju Structural and Biochemical Studies of Inhibitor Binding to Human Cytomegalovirus Protease
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.97: assemblin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 0FP A E31 N62 H63 S132 L133 S134 S135 R136 R137 C161 V163 G164 R165 I231 E28 N53 H54 S123 L124 S125 S126 R127 R128 C144 V146 G147 R148 I205 PDBbind-CN: -logKd/Ki=7.30,IC50<0.05uM
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1nju, PDBe:1nju, PDBj:1nju
PDBsum1nju
PubMed12549906
UniProtP16753|SCAF_HCMVA Capsid scaffolding protein (Gene Name=UL80)

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