Structure of PDB 1nh8 Chain A

Receptor sequence
>1nh8A (length=276) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
MLRVAVPNKGALSEPATEILAEAGYRRRTDSKDLTVIDPVNNVEFFFLRP
KDIAIYVGSGELDFGITGRDLVCDSGAQVRERLALGFGSSSFRYAAPAGR
NWTTADLAGMRIATAYPNLVRKDLATKGIEATVIRLDGAVEISVQLGVAD
AIADVVGSGRTLSQHDLVAFGEPLCDSEAVLIERAEARDQLVARVQGVVF
GQQYLMLDYDCPRSALKKATAITPGLESPTIAPLADPDWVAIRALVPRRD
VNGIMDELAAIGAKAILASDIRFCRF
3D structure
PDB1nh8 Crystal structure of ATP phosphoribosyltransferase from Mycobacterium tuberculosis
ChainA
Resolution1.8 Å
3D
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Enzymatic activity
Enzyme Commision number 2.4.2.17: ATP phosphoribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP A V155 G157 S158 G159 R160 T161 V155 G157 S158 G159 R160 T161
BS02 HIS A D216 Y217 D218 A273 L275 D208 Y209 D210 A265 L267
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003879 ATP phosphoribosyltransferase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016208 AMP binding
GO:0016757 glycosyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0000105 L-histidine biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:1nh8, PDBe:1nh8, PDBj:1nh8
PDBsum1nh8
PubMed12511575
UniProtP9WMN1|HIS1_MYCTU ATP phosphoribosyltransferase (Gene Name=hisG)

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