Structure of PDB 1nde Chain A

Receptor sequence
>1ndeA (length=231) Species: 9606 (Homo sapiens) [Search protein sequence]
DALSPEQLVLTLLEAEPPHVLISRPSFTEASMMMSLTKLADKELVHMISW
AKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVL
DRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYA
TQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVR
HASNKGMEHLLNMKCKPVYDLLLEMLNAHVL
3D structure
PDB1nde A New Series of Estrogen Receptor Modulators That Display Selectivity for Estrogen Receptor beta
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MON A M295 L298 A302 D303 E305 L339 R346 I373 I376 H475 L476 M33 L36 A40 D41 E43 L77 R84 I111 I114 H209 L210 PDBbind-CN: -logKd/Ki=7.82,Ki=15nM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1nde, PDBe:1nde, PDBj:1nde
PDBsum1nde
PubMed12459017
UniProtQ92731|ESR2_HUMAN Estrogen receptor beta (Gene Name=ESR2)

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