Structure of PDB 1nd3 Chain A

Receptor sequence
>1nd3A (length=285) Species: 31708 (rhinovirus A16) [Search protein sequence]
NPVERYVDEVLNEVLVVPNINQSHPTTSNAAPVLDAAETGHTNKIQPEDT
IETRYVQSSQTLDEMSVESFLGRSGCIHESVLDIVDNYNDQSFTKWNINL
QEMAQIRRKFEMFTYARFDSEITMVPSVAAKDGHIGHIVMQYMYVPPGAP
IPTTRDDYAWQSGTNASVFWQHGQPFPRFSLPFLSIASAYYMFYDGYDGD
TYKSRYGTVVTNDMGTLCSRIVTSEQLHKVKVVTRIYHKAKHTKAWCPRP
PRAVQYSHTHTTNYKLSSEVHNDVAIRPRTNLTTV
3D structure
PDB1nd3 Structural and virological studies of the stages of virus replication that are affected by antirhinovirus compounds
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A N1 V3 Y6 E9 D63 S66 E68 S180 K241 H242 N1 V3 Y6 E9 D63 S66 E68 S180 K241 H242
BS02 W11 A I98 Y142 M143 Y144 A166 V168 F179 L181 Y190 M214 I98 Y142 M143 Y144 A166 V168 F179 L181 Y190 M214
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:1nd3, PDBe:1nd3, PDBj:1nd3
PDBsum1nd3
PubMed15452226
UniProtQ82122|POLG_HRV16 Genome polyprotein

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