Structure of PDB 1n9g Chain A

Receptor sequence
>1n9gA (length=364) Species: 5482 (Candida tropicalis) [Search protein sequence]
MITAQAVLYTQHGEPKDVLFTQSFEIDDDNLAPNEVIVKTLGSPINPSDI
NQIQGVYPSKPAKTTGFGTAEPAAPCGNEGLFEVIKVGSNVSSLEAGDWV
IPSHVNFGTWRTHALGNDDDFIKLPNPAQSKANGKPNGLTINQGATISVN
PLTAYLMLTHYVKLTPGKDWFIQNGGTSAVGKYASQIGKLLNFNSISVIR
DRPNLDEVVASLKELGATQVITEDQNNSKEFGPTIKEWIKQSGGEAKLAL
NCVGGKSSTGIARKLNNNGLMLTYGGMSFQPVTIPTSLYIFKNFTSAGFW
VTELLKNNKELKTSTLNQIIAWYEEGKLTDAKSIETLYDGTKPLHELYQD
GVANSKDGKQLITY
3D structure
PDB1n9g Candida tropicalis expresses two mitochondrial 2-enoyl thioester reductases that are able to form both homodimers and heterodimers.
ChainA
Resolution1.98 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y79
Catalytic site (residue number reindexed from 1) Y57
Enzyme Commision number 1.3.1.104: enoyl-[acyl-carrier-protein] reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP A N172 T199 S200 A201 R222 R224 Y296 G297 M299 F321 W322 N150 T177 S178 A179 R200 R202 Y274 G275 M277 F299 W300
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity
GO:0141148 enoyl-[acyl-carrier-protein] reductase (NADPH) activity
Biological Process
GO:0006631 fatty acid metabolic process
GO:0006633 fatty acid biosynthetic process
Cellular Component
GO:0005739 mitochondrion

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1n9g, PDBe:1n9g, PDBj:1n9g
PDBsum1n9g
PubMed12890667
UniProtQ8WZM4|ETR2_CANTR Enoyl-[acyl-carrier-protein] reductase 2, mitochondrial (Gene Name=ETR2)

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