Structure of PDB 1n83 Chain A

Receptor sequence
>1n83A (length=251) Species: 9606 (Homo sapiens) [Search protein sequence]
HHLEVLFQGPAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIEN
YQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGS
LEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSL
CSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKN
HREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKEL
F
3D structure
PDB1n83 X-ray Structure of hROR(alpha) LBD at 1.63A: Structural and Functional data that Cholesterol or a Cholesterol derivative is the natural ligand of ROR(alpha)
ChainA
Resolution1.63 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CLR A W320 K326 I327 M368 F391 F399 W60 K66 I67 M108 F131 F139
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Cellular Component
External links
PDB RCSB:1n83, PDBe:1n83, PDBj:1n83
PDBsum1n83
PubMed12467577
UniProtP35398|RORA_HUMAN Nuclear receptor ROR-alpha (Gene Name=RORA)

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