Structure of PDB 1n6j Chain A

Receptor sequence
>1n6jA (length=93) Species: 9606 (Homo sapiens) [Search protein sequence]
GRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSA
NRLFQYASTDMDRVLLKYTEYSEPHESRTNTDILETLKRRGIG
3D structure
PDB1n6j Sequence-specific recruitment of transcriptional co-repressor Cabin1 by myocyte enhancer factor-2
ChainA
Resolution2.2 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A G2 R3 K5 K31 G1 R2 K4 K30
BS02 dna A G2 R3 K4 I6 R24 K30 G1 R2 K3 I5 R23 K29
BS03 peptide A Q56 D61 D63 L67 Y69 T70 S73 E74 P75 Q55 D60 D62 L66 Y68 T69 S72 E73 P74
Gene Ontology
Molecular Function
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0046983 protein dimerization activity
Biological Process
GO:0045944 positive regulation of transcription by RNA polymerase II

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:1n6j, PDBe:1n6j, PDBj:1n6j
PDBsum1n6j
PubMed12700764
UniProtQ02080|MEF2B_HUMAN Myocyte-specific enhancer factor 2B (Gene Name=MEF2B)

[Back to BioLiP]