Structure of PDB 1n4m Chain A

Receptor sequence
>1n4mA (length=345) Species: 9606 (Homo sapiens) [Search protein sequence]
NTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKRVKDIGYIFKEK
FAKAVGAGCVAIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLND
NIFHMSLLACALEVVMATYSRSTSQNLDSGTDLSFPWILNVLNLKAFDFY
KVIESFIKAEGNLTREMIKHLERCEHRIMESLAWLSDSPLFDLIKQSKTR
EGKSTSLSLFYKKVYRLAYLRLNTLCERLLSEHPELEHIIWTLFQHTLQN
EYELMRDRHLDQIMMCSMYGICKVKNIDLKFKIIVTAYKDLPHAVQETFK
RVLIKEEEYDSIIVFYNSVFMQRLKTNILQYASTRPPTLSPIPHI
3D structure
PDB1n4m Structural basis for the recognition of the E2F transactivation domain by the retinoblastoma tumor suppressor
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A E464 R467 K475 D479 F482 K530 E533 S534 K548 E551 E554 H555 L649 K652 K653 R656 I785 E85 R88 K96 D100 F103 K151 E154 S155 K169 E172 E175 H176 L209 K212 K213 R216 I345
Gene Ontology
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:1n4m, PDBe:1n4m, PDBj:1n4m
PDBsum1n4m
PubMed12502741
UniProtP06400|RB_HUMAN Retinoblastoma-associated protein (Gene Name=RB1)

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