Structure of PDB 1n4a Chain A

Receptor sequence
>1n4aA (length=244) Species: 562 (Escherichia coli) [Search protein sequence]
APRVITLSPANTELAFAAGITPVGVSSYSDYPPQAQKIEQVSTWQGMNLE
RIVALKPDLVIAWRGGNAERQVDQLASLGIKVMWVDATSIEQIANALRQL
APWSPQPDKAEQAAQSLLDQYAQLKAQYADKPKKRVFLQFGINPPFTSGK
ESIQNQVLEVCGGENIFKDSRVPWPQVSREQVLARSPQAIVITGGPDQIP
KIKQYWGEQLKIPVIPLTSDWFERASPRIILAAQQLCNALSQVD
3D structure
PDB1n4a Crystal structures of the BtuF periplasmic-binding protein for vitamin B12 suggest a functionally important reduction in protein mobility upon ligand binding.
ChainA
Resolution2.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CNC A P9 A10 Y28 W44 W63 G65 G66 F140 F146 W174 D220 E223 R224 P9 A10 Y28 W44 W63 G65 G66 F140 F146 W174 D220 E223 R224
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0031419 cobalamin binding
Biological Process
GO:0015889 cobalamin transport
Cellular Component
GO:0016020 membrane
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space
GO:1990191 cobalamin transport complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1n4a, PDBe:1n4a, PDBj:1n4a
PDBsum1n4a
PubMed12468528
UniProtP37028|BTUF_ECOLI Vitamin B12-binding protein (Gene Name=btuF)

[Back to BioLiP]