Structure of PDB 1n3z Chain A

Receptor sequence
>1n3zA (length=119) Species: 9913 (Bos taurus) [Search protein sequence]
KESAAAKFERQHMDSGSSNYCNLMMCCRKMTQGKCKPVNTFVHESLADVK
AVCSQKKVTCKNGQTNCYQSKSTMRITDCRETGSSKYPNCAYKTTQVEKH
IIVACGGKPSVPVHFDASV
3D structure
PDB1n3z The unswapped chain of bovine seminal ribonuclease: Crystal structure of the free and liganded monomeric derivative
ChainA
Resolution1.65 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H12 K41 H119 F120 D121
Catalytic site (residue number reindexed from 1) H12 K36 H114 F115 D116
Enzyme Commision number 4.6.1.18: pancreatic ribonuclease.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 U3P A K41 N44 T45 F120 K36 N39 T40 F115 PDBbind-CN: -logKd/Ki=4.20,Ki=63.2uM
BindingDB: Ki=63200nM
BS02 ADN A A4 C65 A109 V118 H119 A4 C60 A104 V113 H114
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004519 endonuclease activity
GO:0004522 ribonuclease A activity
GO:0004540 RNA nuclease activity
GO:0016829 lyase activity
GO:0042802 identical protein binding
Biological Process
GO:0050830 defense response to Gram-positive bacterium
GO:0051607 defense response to virus
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:1n3z, PDBe:1n3z, PDBj:1n3z
PDBsum1n3z
PubMed12833549
UniProtP00669|RNS_BOVIN Seminal ribonuclease (Gene Name=SRN)

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