Structure of PDB 1n2s Chain A

Receptor sequence
>1n2sA (length=298) Species: 90371 (Salmonella enterica subsp. enterica serovar Typhimurium) [Search protein sequence]
MNILLFGKTGQVGWELQRSLAPVGNLIALDVHSKEFCGDFSNPKGVAETV
RKLRPDVIVNAAAHTAVDKAESEPELAQLLNATSVEAIAKAANETGAWVV
HYSTDYVFPGTGDIPWQETDATSPLNVYGKTKLAGEKALQDNCPKHLIFR
TSWVYAGKGNNFAKTMLRLAKERQTLSVINDQYGAPTGAELLADCTAHAI
RVALNKPEVAGLYHLVAGGTTTWHDYAALVFDEARKAGITLALTELNAVP
TSAYPTPASRPGNSRLNTEKFQRNFDLILPQWELGVKRMLTEMFTTTT
3D structure
PDB1n2s Variation on a Theme of SDR. dTDP-6-Deoxy-L- lyxo-4-Hexulose Reductase (RmlD) Shows a New Mg(2+)-Dependent Dimerization Mode
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.133: dTDP-4-dehydrorhamnose reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAI A G7 G10 Q11 V12 D30 V31 D39 F40 A62 A63 T65 Y102 Y128 K132 T151 V154 G7 G10 Q11 V12 D30 V31 D39 F40 A62 A63 T65 Y102 Y128 K132 T151 V154
Gene Ontology
Molecular Function
GO:0008831 dTDP-4-dehydrorhamnose reductase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0009103 lipopolysaccharide biosynthetic process
GO:0009243 O antigen biosynthetic process
GO:0019305 dTDP-rhamnose biosynthetic process
GO:0045226 extracellular polysaccharide biosynthetic process
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:1n2s, PDBe:1n2s, PDBj:1n2s
PDBsum1n2s
PubMed12057193
UniProtP26392|RMLD_SALTY dTDP-4-dehydrorhamnose reductase (Gene Name=rfbD)

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