Structure of PDB 1n24 Chain A

Receptor sequence
>1n24A (length=534) Species: 38868 (Salvia officinalis) [Search protein sequence]
IRRSGNYQPALWDSNYIQSLNTPYTEERHLDRKAELIVQVRILLKEKMEP
VQQLELIHDLKYLGLSDFFQDEIKEILGVIYNEHKCFHDLYFTALGFRLL
RQHGFNISQDVFNCFKNEKGIDFKASLAQDTKGMLQLYEASFLLRKGEDT
LELAREFATKCLQKKLDEIDENLLLWIRHSLDLPLHWRIQSVEARWFIDA
YARRPDMNPLIFELAKLNFNIIQATHQQELKDLSRWWSRLCFPEKLPFVR
DRLVESFFWAVGMFEPHQHGYQRKMAATIIVLATVIDDIYDVYGTLDELE
LFTDTFKRWDTESITRLPYYMQLCYWGVHNYISDAAYDILKEHGFFCLQY
LRKSVVDLVEAYFHEAKWYHSGYTPSLDEYLNIAKISVASPAIISPTYFT
FANASHDTAVIDSLYQYHDILCLAGIILRLPDDLGTSYFELARGDVPKTI
QCYMKETNASEEEAVEHVKFLIREAWKDMNTAIAAGYPFPDGMVAGAANI
GRVAQFIYLHGDGFGVQHSKTYEHIAGLLFEPYA
3D structure
PDB1n24 Bornyl diphosphate synthase: Structure and strategy for carbocation manipulation by a terpenoid cyclase
ChainA
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R314 W323 I344 D351 D355 S451 V452 A453 R493 D496 T500 E504 Y572 D576 F578
Catalytic site (residue number reindexed from 1) R250 W259 I280 D287 D291 S387 V388 A389 R429 D432 T436 E440 Y508 D512 F514
Enzyme Commision number 4.2.3.116: (+)-camphene synthase.
4.2.3.121: (+)-alpha-pinene synthase.
5.5.1.8: (+)-bornyl diphosphate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D351 D355 D287 D291
BS02 MG A D496 T500 E504 D432 T436 E440
BS03 MG A D351 D355 D287 D291
BS04 BP2 A R314 T348 D351 V452 R493 D496 E504 K512 F578 R250 T284 D287 V388 R429 D432 E440 K448 F514
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0010333 terpene synthase activity
GO:0016829 lyase activity
GO:0016853 isomerase activity
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
GO:0047926 geranyl-diphosphate cyclase activity
GO:0050550 pinene synthase activity
GO:0102703 camphene synthase activity
Biological Process
GO:0016102 diterpenoid biosynthetic process
GO:0016114 terpenoid biosynthetic process
GO:0046211 (+)-camphor biosynthetic process
Cellular Component
GO:0009507 chloroplast

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1n24, PDBe:1n24, PDBj:1n24
PDBsum1n24
PubMed12432096
UniProtO81192|BPPS_SALOF (+)-bornyl diphosphate synthase, chloroplastic

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