Structure of PDB 1n23 Chain A

Receptor sequence
>1n23A (length=533) Species: 38868 (Salvia officinalis) [Search protein sequence]
RRSGNYQPALWDSNYIQSLNTPYTEERHLDRKAELIVQVRILLKEKMEPV
QQLELIHDLKYLGLSDFFQDEIKEILGVIYNEHKCFMDLYFTALGFRLLR
QHGFNISQDVFNCFKNEKGIDFKASLAQDTKGMLQLYEASFLLRKGEDTL
ELAREFATKCLQKKLDEIDENLLLWIRHSLDLPLHWRIQSVEARWFIDAY
ARRPDMNPLIFELAKLNFNIIQATHQQELKDLSRWWSRLCFPEKLPFVRD
RLVESFFWAVGMFEPHQHGYQRKMAATIIVLATVIDDIYDVYGTLDELEL
FTDTFKRWDTESITRLPYYMQLCYWGVHNYISDAAYDILKEHGFFCLQYL
RKSVVDLVEAYFHEAKWYHSGYTPSLDEYLNIAKISVASPAIISPTYFTF
ANASHDTAVIDSLYQYHDILCLAGIILRLPDDLGTSYFELARGDVPKTIQ
CYMKETNASEEEAVEHVKFLIREAWKDMNTAIAAGYPFPDGMVAGAANIG
RVAQFIYLHGDGFGVQHSKTYEHIAGLLFEPYA
3D structure
PDB1n23 Bornyl diphosphate synthase: Structure and strategy for carbocation manipulation by a terpenoid cyclase
ChainA
Resolution2.4 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R314 W323 I344 D351 D355 S451 V452 A453 R493 D496 T500 E504 Y572 D576 F578
Catalytic site (residue number reindexed from 1) R249 W258 I279 D286 D290 S386 V387 A388 R428 D431 T435 E439 Y507 D511 F513
Enzyme Commision number 4.2.3.116: (+)-camphene synthase.
4.2.3.121: (+)-alpha-pinene synthase.
5.5.1.8: (+)-bornyl diphosphate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D351 D355 D286 D290
BS02 MG A D351 D355 D286 D290
BS03 MG A D496 T500 E504 D431 T435 E439
BS04 2BN A T348 V452 F578 T283 V387 F513
BS05 POP A R314 D351 R493 D496 T500 E504 R249 D286 R428 D431 T435 E439
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0010333 terpene synthase activity
GO:0016829 lyase activity
GO:0016853 isomerase activity
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
GO:0047926 geranyl-diphosphate cyclase activity
GO:0050550 pinene synthase activity
GO:0102703 camphene synthase activity
Biological Process
GO:0016102 diterpenoid biosynthetic process
GO:0016114 terpenoid biosynthetic process
GO:0046211 (+)-camphor biosynthetic process
Cellular Component
GO:0009507 chloroplast

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1n23, PDBe:1n23, PDBj:1n23
PDBsum1n23
PubMed12432096
UniProtO81192|BPPS_SALOF (+)-bornyl diphosphate synthase, chloroplastic

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